Experimental browser for the Atmosphere
You thought Glu/Asp don't like RNA or DNA? Maybe you even introduced them into your protein to stop such interactions? 😱🧪 Think again! New paper @angewandtechemie.bsky.social with Wöhnert lab shows structural context matters for phosphodiester interactions! onlinelibrary.wiley.com/doi/10.1002/...
Apr 27, 2025, 12:00 PM
{ "uri": "at://did:plc:sovndmxxrob7lxmbbggn6dgp/app.bsky.feed.post/3lns7c4lpfk2c", "cid": "bafyreibfi2jwqrf3dsdrs4tqirmahpygczlo54xyplag6wpx2pdnukpbbu", "value": { "text": "You thought Glu/Asp don't like RNA or DNA? Maybe you even introduced them into your protein to stop such interactions? \n😱🧪\nThink again! New paper @angewandtechemie.bsky.social with Wöhnert lab shows structural context matters for phosphodiester interactions! \nonlinelibrary.wiley.com/doi/10.1002/...", "$type": "app.bsky.feed.post", "embed": { "$type": "app.bsky.embed.external", "external": { "uri": "https://onlinelibrary.wiley.com/doi/10.1002/anie.202501589", "thumb": { "$type": "blob", "ref": { "$link": "bafkreiawvisnnkahigm2mtddrswbx4tgywsnrszu3vu76er5zhqjda2gju" }, "mimeType": "image/jpeg", "size": 369135 }, "title": "Protonated Glutamate and Aspartate Side Chains Can Recognize Phosphodiester Groups via Strong and Short Hydrogen Bonds in Biomacromolecular Complexes", "description": "Phosphodiester groups occur ubiquitously in nature, e.g. in nucleic acids or in cyclic (di-)nucleotides important for signal transduction. Proteins often use polar or positively charged amino acids t..." } }, "langs": [ "en" ], "facets": [ { "$type": "app.bsky.richtext.facet", "index": { "byteEnd": 181, "byteStart": 152 }, "features": [ { "did": "did:plc:dqtuu74ofjauvkihjay3nfi5", "$type": "app.bsky.richtext.facet#mention" } ] }, { "index": { "byteEnd": 306, "byteStart": 267 }, "features": [ { "uri": "https://onlinelibrary.wiley.com/doi/10.1002/anie.202501589", "$type": "app.bsky.richtext.facet#link" } ] } ], "createdAt": "2025-04-27T12:00:26.822Z" } }