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Cool paper from the Davis lab using human tonsil organoids to study CD4 and CD8 Tregs. Even though subjects with autoimmunity were excluded, organoids derived from female donors had higher autoreactivity, providing an ex vivo system to study sex differences in response to self antigens. #ImmunoSky 🧪

Feb 18, 2025, 4:32 PM

Record data

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    "text": "Cool paper from the Davis lab using human tonsil organoids to study CD4 and CD8 Tregs. Even though subjects with autoimmunity were excluded, organoids derived from female donors had higher autoreactivity, providing an ex vivo system to study sex differences in response to self antigens. #ImmunoSky 🧪",
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        "uri": "https://www.nature.com/articles/s41590-024-02062-x",
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        "title": "Differential roles of human CD4+ and CD8+ regulatory T cells in controlling self-reactive immune responses - Nature Immunology",
        "description": "Here the authors use a tonsil organoid culture model system to investigate the roles of human CD4+ and CD8+ regulatory T cells in controlling self-reactive immune responses. CD4+ regulatory T cells we..."
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