ATProto Browser

ATProto Browser

Experimental browser for the Atmosphere

Post

Is there any discussion of the serious caveats with substituting embeddings for raw data, examined in truly exhaustive detail by Chari et al. years ago? No. But is it at least aware of the scale of sequencing in 2025? Also no, because it talks about the # genes > # cells regime.

Apr 23, 2025, 1:57 AM

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  "text": "Is there any discussion of the serious caveats with substituting embeddings for raw data, examined in truly exhaustive detail by Chari et al. years ago? No. But is it at least aware of the scale of sequencing in 2025? Also no, because it talks about the # genes > # cells regime.",
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      "uri": "https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1011288",
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      "title": "The specious art of single-cell genomics",
      "description": "Dimensionality reduction is standard practice for filtering noise and identifying relevant features in large-scale data analyses. In biology, single-cell genomics studies typically begin with reductio..."
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