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💊 Abatacept Humanized protein construct from recombinant DNA (CTLA4 + IgG1 Fc) grown in hamster ovary cells. Selectively binds to CD80/86 on APCs, inhibiting CD80/86-CD28 costimulatory signal essential for full T-cell activation. #medsky #IMsky #rheumsky #biologics (Herrero-Beaumont et al., 2012)
Feb 6, 2025, 12:21 PM
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